Depending on the state of your immune system and other imbalances, this could take a little time to work. Think about how long you have been wanting to lose weight or get healthy. It’s not magic, your body is trying to come into balance. The Xceler8 has B-12 that gives your body energy. You might want to experiment and not take the Xceler8 after 2:00 PM. The Rejuveniix also will give you energy, so you might want to limit when you take that as well. Most people do well and can take them at any time, but some people are sensitive.